Hereditary Breast-Ovarian Cancer
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Women with hereditary breast cancer predispositions should avoid using their smartphones, tablets and laptops at night
Breast cancer is the most common malignancy among women, both in the developed and developing countries. Women with mutations in the BRCA1 and BRCA2 genes have an increased risk of breast and ovarian cancers. Recent studies show that short-wavelength visible light disturb the secretion of melatonin and causes circadian rhythm disruption. We have previously studied the health effects of exposure...
متن کاملClinical, Molecular and Geographical Features of Hereditary Breast/Ovarian Cancer in Latvia
INTRODUCTION The aim of the study is to evaluate the incidence and phenotype-genotype characteristics of hereditary breast and ovarian cancer syndromes in Latvia in order to develop the basis of clinical management for patients and their relatives affected by this syndrome. MATERIALS AND METHODS In 2002-2004 in two Latvian oncology hospitals (Liepãja Oncology Hospital and Daugavpils Oncology ...
متن کاملThe Prevention of Hereditary Breast and Ovarian Cancer: A Personal View
Options for the prevention of hereditary breast and ovarian cancer include screening, preventive surgery and chemoprevention. Screening studies with magnetic resonance imaging of the breast are promising but the technology is not widespread and MRI is unlikely to be available as a screening tool in the near future. Prophylactic oophorectomy and mastectomy are effective preventive measures and a...
متن کاملHereditary Risk of Breast and Ovarian Carcinoma: The Role of the Oncologist.
The American Society of Clinical Oncology has affirmed the role of clinical oncologists in identifying and managing patients with familial cancer risk. Inherited mutations in the genes BRCA1 and BRCA2 are responsible for the majority of hereditary breast and ovarian cancers, and these mutations also increase the risk of second cancers in women already diagnosed with breast malignancy. Understan...
متن کاملClinical considerations in the management of individuals at risk for hereditary breast and ovarian cancer.
BACKGROUND Hereditary predisposition to breast and ovarian cancer, most commonly due to germline mutations in BRCA1 and BRCA2, has been recognized for many years. The optimal clinical management of individuals with such a predisposition is not yet completely defined. METHODS The current literature regarding the clinical management of individuals at risk for hereditary breast and ovarian cance...
متن کامل[Hereditary breast and ovarian cancer syndrome].
Population with hereditary breast and ovarian cancer syndrome, i.e. BRCA1/2 mutation carriers, are at higher risk of developing breast and ovarian cancer as well as other solid tumours such as pancreatic cancer, prostate cancer and melanoma. With the increasing experience, screening recommendations and preventive strategies including prophylactic surgery are being settled. Surveillance of women...
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